Sedigheh Asad

Journal Paper

1. "Niche-Aware Metagenomic Screening for Enzyme Methioninase Illuminates Its Contribution to Metabolic Syntrophy"
   Erfan khamespanah, Sedigheh Asad, zeynab vanak, ملیحه مهرشاد
   MICROBIAL ECOLOGY, Vol. 87, No 1, 2024
2. "Design of a two functional permeable reactive barrier for synergistic enzymatic and microbial bioremediation of phenol-contaminated waters: laboratory column evaluation"
   Sayed Hossein Mirdamadian, Sedigheh Asad, سید محمد مهدی دستغیب, Hamid Moghimi
   BMC MICROBIOLOGY, Vol. 24, No 252, 2024
3. "Elucidated potential of immobilized Janibacter sp. for saline wastewater phenol removal"
   zeynab vanak, Sedigheh Asad, سید محمد مهدی دستغیب
   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Vol. 107, No 22, pp.6999-7011, 2023
4. "Engineering a Novel Metabolic Pathway for Improving Cellular Malonyl-CoA Levels in Escherichia coli"
   Mohammad Hossein Moteallehi-ardakani, Sedigheh Asad, Sayed Amir Marashi, Sayedeh Afrooz Moghadasi, Parisa Zarparvart
   MOLECULAR BIOTECHNOLOGY, Vol. 1, No 1, 2023
5. "Genome-resolved insight into the reservoir of antibiotic resistance genes in aquatic microbial community"
   [] [], Sedigheh Asad, ملیحه مهرشاد
   Scientific Reports, Vol. 12, No 1, 2022
6. "Knockdown of HSF1 sensitizes resistant prostate cancer cell line to chemotherapy"
   Roya Yousefi, Mahbobe Kabiri, فاطمه کوهکن, Mahshid Heidari, Sedigheh Asad, Simzar Hosseinzadeh, Mohamad Hasan Nazaran
   Modern Medical Laboratory Journal, Vol. 5, No 2, pp.47-55, 2022
7. "Investigating the role of Glu-Ala spacer sequence on the expression and secretion of recombinant uricase in Pichia pastoris"
   sepideh tamimi, Sedigheh Asad, Hamid Moghimi, Seyed Mohammad Mehdi Dastgheib
   current topics in biotechnology, Vol. 12, No 1, 2021
8. "CRISPR/Cas9-mediated TGFβRII disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells in vitro"
   Khadijeh Alishah, Matthias Birtel, Elham Masoumi, Leila Jafarzadeh, Hamid Reza Mirzaee, Jamshid Hadjati, Ralf Holger Voss, Mustafa Diken, Sedigheh Asad
   Journal of Translational Medicine, Vol. 19, No 1, 2021
9. "Chitosan/PEO nanofibers containing Calendula officinalis extract: Preparation, characterization, in vitro and in vivo evaluation for wound healing applications"
   زهرا خراط, Mahdi Amiri, نازنین سرویان, Sedigheh Asad, Mohammad Mehdi Dehghan, Mahbobe Kabiri
   INTERNATIONAL JOURNAL OF PHARMACEUTICS, Vol. 609, No 1, 2021
10. "Horseradish peroxidase-calcium peroxide core–shell microcapsules as a novel permeable reactive barrier for bioremediation of phenol-contaminated waters"
    Sayed Hossein Mirdamadian, Hamid Moghimi, Sedigheh Asad, Seyed Mohammad Mehdi Dastgheib, Farzaneh Karimian
    International Journal of Environmental Science and Technology, Vol. 1-1, pp.1-12, 2021
11. "Enhanced Solubility and One-Step Purification of Functional Dimeric Carboxypeptidase G2"
    Atefeh Khodakarami, Bahareh Dabirmanesh, Sedigheh Asad, mohammad khaledi
    BIOCHEMISTRY-MOSCOW, Vol. 86, No 2, pp.190-196, 2021
12. "Heterologous expression of recombinant urate oxidase using the intein‑mediated protein purification in Pichia pastoris"
    Reyhaneh khaleghi, Sedigheh Asad
    3 Biotech, Vol. 11, No 1, 2021
13. "Metagenomic discovery and functional validation of L-asparaginases with anti-leukemic effect from the Caspian Sea"
    Motahareh Sobat, Sedigheh Asad, Mahbobe Kabiri, ملیحه مهرشاد
    IScience, Vol. 24, No 24, 2021
14. "Optimizing the Production of Soluble Form of Recombinant L-asparaginase isolated from Halophilic Bacterium in Escherichia coli"
    yasaman asaadi, Reyhaneh khaleghi, Sedigheh Asad
    Biology of Microorganisms, Vol. 35, No 1, 2020
15. "Developing a Fluorescent Hybrid Nanobiosensor Based on Quantum Dots and Azoreductase Enzyme forMethyl Red Monitoring"
    Fahimeh Hajipour, Sedigheh Asad, Mohammad Amozegar, ali asghar Javadiparvar, jialun tang, haizheng zhong, Khosro Khajeh
    IRANIAN BIOMEDICAL JOURNAL, Vol. 25, No 1, 2020
16. "Using Saccostrea cucullata as a biomonitor of heavy metals (Cu, Pb, Zn, Cd, Ni, and Cr) in water and sediments of Qeshm Island, Persian Gulf"
    parisa norouzi fard, samar mortazavi, Sedigheh Asad, نسرین حسن زاده
    ECOPERSIA, Vol. 8, No 3, pp.181-190, 2020
17. "Heterologous production of porcine derived antimicrobial peptide PR-39 in Escherichia coli using SUMO and intein fusion systems"
    Mandana azari, Sedigheh Asad, Mohammad Reza Mehrnia
    PROTEIN EXPRESSION AND PURIFICATION, Vol. 169, No 1, 2020
18. "Synthesis of the MPA- Capped CdSe/ZnS Quantum Dots and Study the Quenching Effect of Azo Dyes on Them"
    fahimeh hajipour, Sedigheh Asad, Mohammad Amozegar, Khosro Khajeh
    Modares Journal of Biotechnology, Vol. 10, No 3, 2019
19. "A Study on the Potential of Uricase Production by Halophilic Bacteria and Enzyme Production Optimization"
    Pejman Shirazian, Ali Ghasemi, Sedigheh Asad, Mohammad Amozegar
    Modares Journal of Biotechnology, Vol. 10, No 3, 2019
20. "Toxic Elements Bioavailability from Total Amount in Persian Gulf Surface Sediments"
    parisa norouzi fard, samar mortazavi, Sedigheh Asad, nasrin hasan zadeh
    Tarbiyat Modares, Vol. 8, No 1, pp.359-369, 2019
21. "Improving the thermal stability of azoreductase from Halomonas elongata by introducing a disulfide bond via site-directed mutagenesis"
    Narjes Nakhaee, Sedigheh Asad, Khosro Khajeh, سیدشهریار عرب , Mohammad Amozegar
    BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, Vol. 1, No 1, 2018
22. "Exploring the potential of halophilic archaea for the decolorization of azo dyes"
    Masoomeh Selseleh, Mohammad Amozegar, Sedigheh Asad, Maryam Siroosi
    WATER SCIENCE AND TECHNOLOGY, Vol. 77, No 6, pp.1602-1611, 2018
23. "Cloning and characterization of Halomonas elongata L-asparaginase, a promising chemotherapeutic agent"
    Ali Ghasemi, Sedigheh Asad, Mahbobe Kabiri, Bahareh Dabirmanesh
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Vol. 101, No 19, pp.7227-7238, 2017
24. "Genome-scale reconstruction of the metabolic network in Pseudomonas stutzeri A1501"
    Parizad Babaei, Sayed Amir Marashi, Sedigheh Asad
    Molecular BioSystems, Vol. 11, No 11, pp.3022-3032, 2016
25. "Utilizing Intein-mediated Protein Cleaving for Purification of Uricase, A Multimeric Enzyme"
    Khadijeh Alishah, Sedigheh Asad, Khosro Khajeh, Neda Akbari
    ENZYME AND MICROBIAL TECHNOLOGY, Vol. 1, No 1, pp.1-21, 2016
26. "THE POTENTIAL OF HALOPHILIC AND HALOTOLERANT BACTERIA FOR THE PRODUCTION OF ANTINEOPLASTIC ENZYMES: L-ASPARAGINASE AND L-GLUTAMINASE"
    Pejman Shirazian, Sedigheh Asad, Mohammad Amozegar
    EXCLI Journal, Vol. 15, pp.268-279, 2016
27. "Isolation, cloning and characterization of an azoreductase from the halophilic bacterium Halomonas elongata"
    Maryam Eslami, Mohammad Amozegar, Sedigheh Asad
    International Journal of Biological Macromolecules, Vol. 85, No 4, pp.111-116, 2015
28. "Construction of a horseradish peroxidase resistant towards hydrogen peroxide by saturation mutagenesis"
    Sedigheh Asad, Seyed Mohammad Mehdi Dastgheib, Khosro Khajeh
    BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, Vol. 63, No 6, pp.1-6, 2015
29. "Optimization for decolorization of azo dye Remazol Black by a Halomonas strain using the Taguchi approach"
    Sedigheh Asad, Seyed Mohammad Mehdi Dastgheib, Mohammad Amozegar
    Progress in Biological Sciences, Vol. 4, No 1, pp.33-42, 2014
30. "Phenol removal from refinery wastewater by mutant recombinant horseradish peroxidase"
    Sedigheh Asad, Bahareh Dabirmanesh, خسرو خواجه
    BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, Vol. 61, No 2, pp.226-229, 2014
31. "Studies on the Refolding Process of Recombinant Horseradish Peroxidase"
    Sedigheh Asad, Bahareh Dabirmanesh , Naser Ghaemi, Seyed Masoud Etezad , Khosro Khajeh
    MOLECULAR BIOTECHNOLOGY, Vol. -, 2012
32. "Azo dye decolorization by halophilic and halotolerant microorganisms"
    Mohammad Amozegar, Mahbod Hajighasemi , Javad Hamedi, Sedigheh Asad, Antonio Ventosa
    ANNALS OF MICROBIOLOGY, Vol. 61, No 2, pp.217-230, 2011
33. "Investigating the Structural and Functional Effects of Mutating Asn Glycosylation Sites of Horseradish Peroxidase to Asp"
    Sedigheh Asad, Khosro Khajeh , Naser Ghaemi
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, Vol. 164, No 4, pp.454-463, 2011
34. "Phosphate buffer effects on thermal stability and H2O2 - resistance of horseradish peroxidase"
    Sedigheh Asad, S F Torabi , M Fathi Roudsari , Naser Ghaemi, K Khajeh
    International Journal of Biological Macromolecules, Vol. 48, No 4, pp.566-570, 2011
35. "Bioemulsifier production by a halothermophilic Bacillus strain with potential applications in microbially enhanced oil recovery"
    S.m.m Dastgheib, Mohammad Amozegar, Elahe Allahi, Sedigheh Asad, Ibrahim Mohamed Banat
    BIOTECHNOLOGY LETTERS, Vol. 30, No 2, pp.263-270, 2008
36. "Decolorization of textile azo dyes by newly isolated halophilic and halotolerant bacteria"
    Sedigheh Asad, M A Amoozegar , A A Pourbabaee , Mohammad Nabi Sar Bouloki, S M M Dastgheib
    BIORESOURCE TECHNOLOGY, Vol. 98, No 11, pp.2082-2088, 2007
37. "The role of glycans in the structure and function of the SARS-Cov-2 spike protein (Covid19)"
    [] [], Sedigheh Asad
    Modares Journal of Biotechnology, Vol. 14, No 3, 2023
38. "Improved phenol removal in saline effluents by immobilized bacteria"
    zeynab vanak, Sedigheh Asad, سید محمد مهدی دستغیب
    Modares Journal of Biotechnology, Vol. 14, No 1, 2023
39. "Estimation of toxicity and ecological risk of toxic elements using biomarkers in north coastal sediments of the Persian Gulf in Hormozgan province"
    parisa norouzi fard, ثمر مرتضوی, Sedigheh Asad, نسرین حسن زاده
    Journal of Aquatic Ecology, Vol. 9, No 2, pp.46-60, 2019
40. "HEAVY metal content of sediments; MARINE sediments; HEAVY metals; ECOSYSTEM health; PERCHLORIC acid; NITRIC acid"
    parisa norouzi fard, samar mortazavi, Sedigheh Asad, nasrin hasan zadeh
    Iranian Journal of Health and Environment, Vol. 3, No 11, 2018
41. "Evaluation of biodecolarization of the textile azo dye by halophilic archaea"
    Masoomeh Selseleh Hassan-kiadehi, Mohammad Amozegar, Sedigheh Asad
    Biology of Microorganisms, Vol. 6, No 23, pp.1-17, 2017
42. "Evaluation of biological decolorization of the textile azo-dyes by halophilic and halotolerant actinomycetes"
    Farzaneh Mahdavi Zafarghandi, Mohammad Amozegar, Sedigheh Asad, Maryam Siroosi
    Color Science and Technology, Vol. 11, No 2, pp.145-152, 2017
43. "avaluation of capability of taguchi method in microbial medium design: optimization of alpha-amylase production by statistical design of experiments"
    داود زارع , مهرداد آذین , Sedigheh Asad, سید محمد مهدی دستغیب , حسینعلی اصغریان , محبوبه کبیری
    Biological Science Promotion, Vol. 23/3, 2010
44. "Effects of various factors on the decolorization of textile azo dyes by newly isolated halophilic and halotolerant bacteria"
    Sedigheh Asad, Mohammad Amozegar, Mohammad Nabi Sar Bouloki, احمدعلی پوربابایی, Seyed Mohammad Mehdi Dastgheib
    Biological Science Promotion, Vol. 21, No 1, pp.5-16, 2008

Conference Paper

1. "Comparative genomics of 919 microbial genomes of the order Oceanospirillales for oil hydrocarbon degradation"
   Fateme Qasemnejad, Sedigheh Asad, سید محمد مهدی دستغیب, ملیحه مهرشاد
   3rd international and 12th iranian conference on Bioinformatics, 2024
2. "Novel functionally validated L-asparaginases with anti-proliferating activity against leukemic cell line: A MetaGenomic survey in Caspian Sea"
   Mahbobe Kabiri, Sedigheh Asad, Motahareh Sobat, Maliheh Mehrshad
   International Conference on Human Genetics and Genomics, 2021
3. "Preparation, evaluation and in vivo assessment of nanofibers containing herbal extracts with antibacterial agents to prevent and control bacterial infection with Staphylococcus aureus"
   Mahbobe Kabiri, زهرا خراط, Sedigheh Asad, نازنین سرویان, Mohammad Mehdi Dehghan
   12th national and 4th international biotechnology congress, 2021
4. "CRISPR/Cas9-mediated TβRII disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells in vitro"
   Khadijeh Alishah, Ralf Holger Voss, Mustafa Diken, Matthias Birtel, Sedigheh Asad, Jamshid Hadjati, ugur sahin
   18th CIMT annual meeting, 2021
5. "Cloning and Cytosolic Expression of Recombinant Urate oxidase in Pichia pink"
   Delara Soltan Esmaeili, Sedigheh Asad
   3rd International & 11th National Biotechnology Congress of Islamic Republic of Iran, 2019
6. "A metabolic network analysis toward model-driven medium optimization for enhancement of recombinant uricase expression in Escherichia coli"
   Najmeh Seyedkatooli, Sedigheh Asad, Sayed Amir Marashi, Khosro Khajeh
   3rd International & 11th National Biotechnology Congress of Islamic Republic of Iran, 2019
7. "Cloning and expression of L-asparaginase based on Caspian Sea metagenomics data analysis"
   Motahareh Sobat, Sedigheh Asad, ملیحه مهرشاد , Mahbobe Kabiri
   3rd International & 11th National Biotechnology Congress of Islamic Republic of Iran, 2019
8. "Identification and extraction of L-asparaginases through large-scale screening of Caspian Sea metagenomics data"
   Motahareh Sobat, ملیحه مهرشاد , Sedigheh Asad, Khadijeh Alishah
   Annual Conference of the Association for General and Applied Microbiology, 2019
9. "Comparison of the Cytosolic and Secreted Expression of Recombinant Urate oxidase in Pichia pastoris"
   Reyhaneh khaleghi, Sedigheh Asad, Khadijeh Alishah
   Annual Conference of the Association for General and Applied Microbiology, 2019
10. "Studies on the Importance of Leader Sequence in the Expression and Secretion of Recombinant Uricase in Pichia pastoris"
    sepideh tamimi, Hamid Moghimi, Sedigheh Asad, Seyed Mohammad Mehdi Dastgheib, Khadijeh Alishah
    Annual Conference of the Association for General and Applied Microbiology, 2019
11. "Studies on the effects of point mutations on the stability of azoreductase from Halomonas elongata"
    Narjes Nakhaee, Sedigheh Asad, Khosro Khajeh, سیدشهریار عرب, Mohammad Amozegar
    2nd international and 10th national biotechnology congress of Islamic republic of Iran, 2017
12. "Evaluating anti-cancer properties of recombinant L-asparaginase of Halomonas Elongata"
    Ali Ghasemi, Sedigheh Asad, Mahbobe Kabiri, Bahareh Dabirmanesh
    2nd international and 10th national biotechnology congress of Islamic republic of Iran, 2017
13. "The role of HSF1 on growth and drug resistance of prostate cancer cell line"
    Roya Yousefi, Mahbobe Kabiri, Fatemeh Koohkan, Sedigheh Asad
    The second international congress on stem cell and regenerative medicine, 2017
14. "Purification of a multimeric enzyme carboxypeptidase G2 by intein -mediated protein splicing"
    Atefeh Khodakarami, Bahareh Dabirmanesh , Sedigheh Asad, Khosro Khajeh
    international congress on Medicine, Public health and biological sciences(MPHBS), 2016
15. "A Novel L-asparaginase Candidate for Acute Lymphoblastic Leukemia Treatment (ALL)"
    Ali Ghasemi, Sedigheh Asad, Mahbobe Kabiri, Bahareh Dabirmanesh
    Royan International Twin Congress 12th Congress on Stem Cell Biology and Technology, 2016
16. "intein mediated gene cloning, expression and purificationof carboxypeptidase G2"
    Atefeh Khodakarami, Bahareh Dabirmanesh , Khosro Khajeh, Sedigheh Asad
    19th national and 17th international congress of biology, 2016
17. "Study of biodecolorization of the textile azo dye by extreme halophile bacteria isolated from a textile effluents"
    Masoomeh Selseleh, Mohammad Amozegar, Sedigheh Asad
    The 16th international and iranian congress of microbiology, 2015
18. "Genome-Scale Metabolic Network of Pseudomonas stutzeri A1501: Reconstruction and Experimental Validation"
    Parizad Babaei, Sayed Amir Marashi, Sedigheh Asad
    5th Iran Conference on Bioinformatics, 2014
19. "Isolating biosurfactant producing microflora of petroleum reservoirs capable of tolerating high salinity and temperature"
    Mohammad Amozegar, مهدی دستغیب, افشین احمدیان, Sedigheh Asad
    Extremophiles 2006, 2006
20. "Identification of halotolerant bioemulsifier producing bacteria from persian oil fields"
    Mohammad Amozegar, سیدمحمد مهدی دستغیب , Elahe Allahi, Sedigheh Asad, رضا کلهر
    FEMS congress of europian microbiologist, 2006
21. "Identification of halophilic azo dye degrading bacteria from textile effluents in salty soils of Iran"
    Mohammad Amozegar, Sedigheh Asad, Mohammad Nabi Sar Bouloki, Ahmad Ali Pourbabaee, سیدمحمد مهدی دستغیب
    FEMS congress of Europian Microbiologist, 2006
22. "Production and identification of a recombinant L-aasparaginase from a halophilic Vibrio sp."
    Sareh Sadat Moosavi natanzi, Sedigheh Asad, Solat Eslami
    5th Interational & 13th National Biotechnology Congress, 2023
23. "Phenol bioremediation in the presence of alginate coated oxygen releasing compounds"
    Sayed Hossein Mirdamadian, Sedigheh Asad, Hamid Moghimi, Seyed Mohammad Mehdi Dastgheib, فرزانه کریمیان
    12th National And 4th International Biotechnology Congress of Islamic Republic of Iran, 2021
24. "Screening of novel arginine deiminase enzyme via large scale analyses of Caspian Sea metagenomes"
    Amir Dargahzadeh, Sedigheh Asad, ملیحه مهرشاد
    12th National And 4th International Biotechnology Congress of Islamic Republic of Iran, 2021
25. "Evaluating the in vitro anti-tumor activity of Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells"
    Khadijeh Alishah, Sedigheh Asad, Jamshid Hadjati
    12th National And 4th International Biotechnology Congress of Islamic Republic of Iran, 2021
26. "Application of HRP and calcium peroxide nanoparticles containing microcapsules for elimination of phenol from contaminated waters"
    Sayed Hossein Mirdamadian, Hamid Moghimi, Sedigheh Asad, Seyed Mohammad Mehdi Dastgheib, فرزانه کریمیان
    3rd Iran water and wastewater science and engineering congress, 2020
27. "Heavy metal risk assessment in aquatic ecosystems based on water quality control indicators"
    parisa norouzi fard, ثمر مرتضوی, Sedigheh Asad, نسرین حسن زاده
    UNESCO RCOWA, 2017
28. "The crisis of the presence of heavy metals in the ecosystem of aquatic organisms and its removal methods"
    parisa norouzi fard, ثمر مرتضوی, Sedigheh Asad, نسرین حسن زاده
    UNESCO RCOWA, 2017
29. "A review on the heavy metal pollution in the aquatic environment of the Persian Gulf"
    parisa norouzi fard, ثمر مرتضوی, Sedigheh Asad, نسرین حسن زاده
    UNESCO RCOWA, 2017
30. "Metabolic engineering of E. coli for increasing malonyl-CoA as the limiting metabolite in phenylpropanoid production pathway"
    Mohammad Hosein Moteallehi, Sayed Amir Marashi, Sedigheh Asad
    2nd international and 10th national biotechnology congress of Islamic republic of Iran, 2017
31. "utilization of intein-mediated protein splicing for the purification of uricase"
    Khadijeh Alishah, Sedigheh Asad, Khosro Khajeh, Neda Akbari
    first international and 9th iranian Biotechnology congress, 2015
32. "Screening of L-glutaminase producing halophilic bacteria and media optimization by response surface methodology"
    Pejman Shirazian, Sedigheh Asad, Mohammad Amozegar
    15th international and iranian congress of microbiology, 2014
33. "molecular cloning and characterization of the gene coding for azoreductase from Halomonas elongata DSM 2581"
    Maryam Eslamy, Mohammad Amozegar, Sedigheh Asad
    15th international iranian conference of microbiology, 2014
34. "studies on the potential of moderately halophilic bacteria for the production of drug enzymes"
    Sedigheh Asad, Pejman Shirazian, Mohammad Amozegar
    First international and 13th iranian genetics congress, 2014
35. "Screening and isolation of halophilic bacteria producing extracellular l-asparaginase from Urmia salt lake"
    Sedigheh Asad, Pejman Shirazian, Mohammad Amozegar
    first international and 13th iranian genetics congress, 2014
36. "Studies on the effects of site directed mutagenesis on the properties of Horseradish peroxidase"
    Sedigheh Asad, خسرو خواجه, Naser Ghaemi
    7th national biotechnology congress of I.R. Iran, 2011
37. "Application of halophilic and halotolerant bacteria in clean up of textile dye mill effluents"
    Sedigheh Asad, Mohammad Amozegar, Mohammad Nabi Sar Bouloki, Ahmad Ali Pourbabaee
    4th Conference of Biothecnology in Iran, 2005